
IMAGEN
Overview
Aims
The IMAGEN study is a large‐scale, longitudinal, imaging genetic study that combines brain imaging, genetics, and psychiatry to increase our understanding of adolescent brain development and behaviour – namely, sensitivity to rewards, impulsivity, and emotional processing. Research teams from London, Nottingham, Dublin, Paris, Berlin, Hamburg, Mannheim and Dresden have been following 2,000 young people and their parents from the age of 14, collecting data from brain imaging, cognitive and behavioural assessments, questionnaires and blood sampling.
Institution
Institute of Psychiatry, Psychology & Neuroscience (IoPPN), King's College London
Geographic coverage - Nations
England
Ireland, France, Germany
Geographic coverage - Regions
London; Nottingham
Start date
2007
Website
imagen-project.org/heaf
Catalogue record last updated
12/05/2026
Sample
Sample type
Cohort study
Sample details
Participants were recruited from high schools at age 14. To obtain a diverse sample in terms of socio-economic status, emotional and cognitive development, private, state-funded and special units were targeted equally. To maximize ethnic (Caucasian) homogeneity, at each study centre recruitment focused on geographical areas with minimal ethnic diversity. Full inclusion and exclusion criteria are detailed in Schumann and colleagues (2010).
Sample size at recruitment
2,000
Sample size at most recent sweep
Approximately 1,200 (2019 - Third Follow-Up)
Sex
All
Age at recruitment
14 years
Cohort year of birth
1993
Mental health measures timeline
Sweep name:
Cohort member age:
Data collection period:
Notes:
Physical health measures:
Key papers
The IMAGEN study: Reinforcement-related behaviour in normal brain function and psychopathology.doi.org/10.1038/mp.2010.4 The IMAGEN study: a decade of imaging genetics in adolescents.doi.org/10.1038/s41380-020-0822-5








